Program 29 September 2023

08.30-9.15 | Targeting defects in DNA repair in precision oncology | Sven Rottenberg
09.15-10.15 | Implementation of the Weight of Evidence Assessment of human carcinogenic risk assessment according to ICHS1B(R1) – presentations and discussion / Thomas Nolte, Susanne Brendler-Schwaab, John Vahle.

10.15-10.45 | COFFEE BREAK - POSTERS – EXHIBITION

10.45-11.15 | Impuritites in Bx and Gene therapies, safety perspective | Helen Booler & Thierry Flandre
11.15-11.45 | Immunogenicity of AAV-based gene therapy and new generation biologics | Fraser McBlane & Hannah Morgan
11.45-12.15 | Pathology readouts of complex in vitro models in safety assessments | Nadine Stokar

12.15-12.35 | Case Presentation: Direct Brain Delivery - Thinking Outside the Box | Deepa Rao
12.35-12.55| Case Presentation: Healthy appearing cynomolgus monkeys presented gross lesions suggesting a generalized granulomatous disease. All previously performed testing (PCR, Mantoux) revealed negative results. What went wrong? | Klaus Weber
12.55-13.10 | Closing Ceremony

13.10-14.00 | Networking Lunch